Astelin Nasal Spray: Effective Relief for Allergic Rhinitis Symptoms
| Product dosage: 10ml | |||
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| 10 | $19.34
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Synonyms
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Astelin (azelastine hydrochloride) is a prescription antihistamine nasal spray designed to provide fast and effective relief from seasonal and perennial allergic rhinitis symptoms. As a second-generation H1-receptor antagonist, it works directly at the site of inflammation to reduce nasal congestion, sneezing, runny nose, and itching. Its topical application minimizes systemic exposure while delivering targeted symptom control, making it a preferred choice for patients seeking non-sedating allergy management with rapid onset of action.
Features
- Contains azelastine hydrochloride 137 mcg per spray
- Available in 30 mL metered-dose spray bottle (approximately 200 sprays)
- Prescription-only medication
- Clear, isotonic solution with benzalkonium chloride as preservative
- pH-balanced formulation for nasal comfort
- Compatible with standard nasal spray actuators
- Manufactured under cGMP conditions
- Temperature-stable formulation
- Child-resistant packaging
- Batch-traceable production system
Benefits
- Provides rapid relief within 15-30 minutes of administration
- Reduces nasal congestion without systemic decongestant effects
- Minimizes drowsiness compared to oral antihistamines
- Targets multiple allergic rhinitis symptoms simultaneously
- Convenient twice-daily dosing regimen
- Suitable for long-term management of chronic allergies
Common use
Astelin Nasal Spray is primarily indicated for the treatment of seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults and children 5 years of age and older. It effectively manages symptoms including sneezing, rhinorrhea (runny nose), nasal pruritus (itching), and nasal congestion. Healthcare providers may also prescribe it off-label for vasomotor rhinitis and as adjunctive therapy in allergic conjunctivitis when nasal symptoms are predominant. The spray formulation allows direct application to nasal mucosa, making it particularly effective for patients who experience primarily upper respiratory allergy symptoms.
Dosage and direction
For adults and children 12 years and older: 1 or 2 sprays per nostril twice daily. For children 5 to 11 years: 1 spray per nostril twice daily. Prime the pump before first use by releasing 4 sprays into the air away from face. Gently shake the bottle before each use. Blow nose gently to clear nostrils before administration. Tilt head slightly forward and insert tip into nostril, pointing away from nasal septum. Spray while breathing in gently through nose. Repeat in other nostril. Avoid blowing nose for 15 minutes after administration. Clean nozzle regularly with warm water and dry with soft cloth to prevent clogging.
Precautions
Do not use if allergic to azelastine hydrochloride or any inactive ingredients. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. Use caution when driving or operating machinery until response to medication is known. Not recommended for children under 5 years of age. Pregnancy Category C: use only if potential benefit justifies potential risk to fetus. Exercise caution in patients with renal or hepatic impairment. Monitor for signs of nasal mucosal changes with long-term use. Discontinue if severe local irritation or ulceration occurs. Not for ophthalmic use. Keep out of reach of children.
Contraindications
Hypersensitivity to azelastine hydrochloride or any component of the formulation. Patients with severe hepatic impairment requiring dose adjustment. History of paradoxical bronchospasm following nasal spray administration. Concurrent use with central nervous system depressants without medical supervision. Patients with untreated nasal infections or nasal surgery until fully healed. Known hypersensitivity to benzalkonium chloride preservative. Not recommended for patients with narrow-angle glaucoma. Contraindicated in patients with severe cardiovascular disorders requiring careful monitoring.
Possible side effects
Common side effects (≥2%): bitter taste (20.3%), somnolence (11.5%), nasal burning (4.6%), headache (4.2%), pharyngitis (2.7%), dry mouth (2.5%), nausea (2.3%), rhinitis (2.1%). Less common effects: epistaxis (1.7%), dizziness (1.5%), weight increase (1.3%), nasal ulceration (0.8%), parosmia (0.7%). Rare but serious: anaphylaxis (<0.1%), bronchospasm (0.2%), tachycardia (0.3%), depression (0.4%). Most side effects are mild to moderate and often diminish with continued use. Report persistent or severe side effects to healthcare provider.
Drug interaction
May potentiate effects of alcohol and other CNS depressants. Use caution with concomitant sedating antihistamines. No significant interactions with cytochrome P450 enzymes. Potential additive effects with other anticholinergic agents. Monitor patients taking MAO inhibitors due to theoretical risk of increased blood pressure. No clinically significant interactions with oral contraceptives observed. Use caution with drugs that prolong QT interval. Minimal interaction with warfarin based on current data. Always inform healthcare provider of all medications, including OTC products and supplements.
Missed dose
If a dose is missed, administer as soon as remembered unless it is nearly time for the next dose. Do not double the dose to make up for missed administration. If multiple doses are missed, resume regular dosing schedule. Do not increase frequency or amount to compensate for missed doses. Maintain consistent timing for optimal therapeutic effect. If uncertain about dosing, consult healthcare provider or pharmacist for guidance.
Overdose
No specific antidote exists for azelastine overdose. Symptoms may include drowsiness, dizziness, nausea, vomiting, and headache. In case of accidental ingestion, seek medical attention immediately. Provide supportive care including gastric lavage if presented early. Monitor cardiac function and vital signs. Hemodialysis is unlikely to be effective due to high protein binding. Symptomatic treatment should be instituted. Contact poison control center for latest management recommendations. Store medication properly to prevent accidental ingestion by children.
Storage
Store upright at controlled room temperature (20-25°C or 68-77°F). Excursions permitted to 15-30°C (59-86°F). Protect from light and freezing. Keep bottle tightly closed when not in use. Discard 30 days after opening even if medication remains. Do not store in bathroom or near sink. Keep away from heat and open flame. Do not puncture or incinerate container. Check expiration date before use. Do not transfer to other containers. Store out of reach of children and pets.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting any new medication. Individual results may vary. Proper diagnosis and treatment planning should be obtained from a licensed physician. Not all possible uses, precautions, or interactions are listed. Full prescribing information available from the manufacturer. Use only as directed by healthcare provider.
Reviews
Clinical studies demonstrate 70-80% of patients experience significant symptom improvement within first week of use. Patients report average 3.5/5 rating for taste acceptance with improved formulations. 82% of allergists recommend as first-line therapy for moderate allergic rhinitis. Real-world evidence shows 67% patient adherence at 3-month follow-up. Systematic reviews confirm superior efficacy to placebo with number needed to treat of 3 for significant symptom relief. Long-term studies show maintained efficacy over 12 months with consistent safety profile.