Bactroban Ointment 5g is a prescription topical antibiotic containing mupirocin 2% w/w. It is specifically formulated for the treatment of bacterial skin infections, including impetigo, folliculitis, and secondary infected traumatic lesions. As a potent antimicrobial agent, it targets key pathogens such as Staphylococcus aureus and Streptococcus pyogenes. Its ointment base ensures targeted delivery and provides a protective barrier to support the healing process.

Features

• Contains mupirocin 2% w/w as the active ingredient
• Presented in a 5g tube for precise, hygienic application
• White, translucent, water-soluble polyethylene glycol base
• Bactericidal action against Gram-positive bacteria
• Minimal systemic absorption when applied topically
• Preservative-free formulation

Benefits

• Effectively eliminates common skin infection-causing bacteria
• Reduces symptoms such as redness, swelling, and exudate
• Helps prevent the spread of infection to other areas or individuals
• Supports faster healing of impaired skin integrity
• Minimizes risk of recurrence when used as directed
• Convenient, localized treatment with low risk of systemic side effects

Common use

Bactroban Ointment is primarily indicated for the topical treatment of impetigo, a contagious superficial skin infection characterized by honey-colored crusts. It is also used for folliculitis, infected eczema, and small, localized wounds that have become secondarily infected with susceptible bacteria. Healthcare providers may also prescribe it for eradication of nasal carriage of Staphylococcus aureus in specific patient populations, though this is an off-label use requiring medical supervision.

Dosage and direction

Apply a small amount of Bactroban Ointment to the affected area three times daily (approximately every 8 hours). The area may be covered with a gauze dressing if desired. Wash hands before and after application unless the hands are the treated area. For impetigo, treatment typically continues for 7–10 days. For nasal use (if prescribed for decolonization), apply half the length of the tube into each nostril twice daily for 5 days. Do not use for longer than 10 days without medical advice.

Precautions

Use only on the skin or intranasally as directed. Avoid contact with eyes, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use on large open wounds, severe burns, or extensive areas of skin breakdown without medical supervision. Use with caution in patients with moderate or severe renal impairment, although systemic absorption is minimal. Discontinue use if sensitization or severe irritation occurs. Not for ophthalmic, intravaginal, or internal use.

Contraindications

Bactroban Ointment is contraindicated in patients with known hypersensitivity to mupirocin or any other component of the formulation. It should not be used in cases where the infection is suspected to be viral or fungal in origin. Avoid use in patients with a history of allergic contact dermatitis to polyethylene glycol. Not recommended for use in the external ear canal if the eardrum is perforated.

Possible side effect

Common side effects include localized burning, stinging, or pain at the application site; itching; dryness; and erythema. Less frequently, patients may experience nausea, headache, or rash. Allergic contact dermatitis has been reported in some cases. Very rare side effects include systemic reactions such as angioedema or generalized urticaria, which require immediate discontinuation and medical attention.

Drug interaction

Formal drug interaction studies have not been conducted due to low systemic absorption. However, concurrent use with other topical products (e.g., corticosteroids, emollients, other antimicrobials) may alter the absorption, efficacy, or irritation potential of Bactroban. If using multiple topical agents, apply Bactroban first and allow it to absorb before applying other products, or as directed by a healthcare provider. Avoid concomitant use with chlorhexidine-containing products as inactivation of mupirocin may occur.

Missed dose

If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not apply a double dose to make up for the missed application. Consistent application supports optimal bacterial eradication and clinical outcomes.

Overdose

Topical overdose is unlikely due to minimal systemic absorption. However, excessive application may lead to increased local adverse effects such as severe irritation, redness, or pain. In case of accidental ingestion, seek medical attention immediately. Symptoms of oral ingestion may include gastrointestinal upset. There is no specific antidote; treatment should be symptomatic and supportive.

Storage

Store at room temperature (15–30°C). Do not freeze. Keep the tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Keep out of reach of children and pets. Do not use after the expiration date printed on the tube. Discard any remaining product after the prescribed treatment course to avoid inadvertent reuse or contamination.

Disclaimer

This information is intended for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before using any medication, especially if pregnant, breastfeeding, or managing underlying health conditions. Use strictly as prescribed; do not self-diagnose or self-medicate.

Reviews

Clinical studies and post-marketing surveillance indicate high efficacy and good tolerability for Bactroban Ointment in treating localized skin infections. Patients and clinicians frequently report rapid improvement in symptoms, ease of application, and low incidence of adverse effects. Some users note a slight greasy residue, though this is characteristic of ointment formulations. Overall, it remains a trusted first-line option for uncomplicated bacterial skin infections.