Indocin: Targeted Relief for Inflammation and Pain
| Product dosage: 25mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 90 | $0.50 | $45.01 (0%) | 🛒 Add to cart |
| 180 | $0.40 | $90.02 $72.02 (20%) | 🛒 Add to cart |
| 270 | $0.37 | $135.03 $99.02 (27%) | 🛒 Add to cart |
| 360 | $0.35
Best per pill | $180.04 $125.03 (31%) | 🛒 Add to cart |
| Product dosage: 50mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 60 | $0.82 | $49.01 (0%) | 🛒 Add to cart |
| 90 | $0.69 | $73.52 $62.01 (16%) | 🛒 Add to cart |
| 120 | $0.62 | $98.02 $74.02 (24%) | 🛒 Add to cart |
| 180 | $0.54 | $147.03 $98.02 (33%) | 🛒 Add to cart |
| 270 | $0.51 | $220.55 $137.03 (38%) | 🛒 Add to cart |
| 360 | $0.49
Best per pill | $294.06 $175.04 (40%) | 🛒 Add to cart |
Indocin (indomethacin) is a potent nonsteroidal anti-inflammatory drug (NSAID) specifically formulated to manage moderate to severe inflammatory conditions. As a prescription medication, it works by inhibiting prostaglandin synthesis, effectively reducing inflammation, pain, and fever. It is commonly indicated for a range of rheumatic diseases, acute gouty arthritis, and ankylosing spondylitis, offering patients a clinically proven option for symptom control. Its efficacy is supported by decades of use in both acute and chronic settings, under appropriate medical supervision.
Features
- Active ingredient: Indomethacin
- Available in 25 mg and 50 mg capsules, as well as 75 mg extended-release capsules
- Also supplied as oral suspension and suppository formulations for flexible administration
- Prescription-only medication requiring healthcare provider authorization
- Manufactured under strict pharmaceutical quality control standards
- Typically packaged in bottles of 30, 60, or 100 units, depending on formulation
Benefits
- Provides significant reduction in inflammation and associated pain in conditions like rheumatoid arthritis and osteoarthritis
- Helps decrease joint stiffness and improve mobility, enhancing quality of life
- Effective in managing acute gout flares by lowering uric acid crystallization and inflammation
- Can reduce fever in certain inflammatory states
- May decrease dependency on opioid analgesics for pain management when used appropriately
- Supports long-term disease management when part of a comprehensive treatment plan
Common use
Indocin is primarily prescribed for inflammatory and painful conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used for acute gouty arthritis, bursitis, tendinitis, and, in some cases, to close a patent ductus arteriosus in premature infants (though this use is highly specialized and administered in hospital settings). Off-label uses may include treatment for certain types of headaches or pericarditis, though these are determined on a case-by-case basis by a healthcare provider.
Dosage and direction
Dosage varies based on the condition being treated, its severity, and patient response. For adults with rheumatoid arthritis, the typical starting dose is 25 mg two or three times daily, which may be increased to a maximum of 150–200 mg per day. For acute gout, 50 mg three times daily is common until pain is tolerable. Extended-release capsules are generally taken once or twice daily. It should be taken with food or milk to minimize gastrointestinal upset. Always follow the specific instructions provided by the prescribing physician, and do not adjust dosage without consultation.
Precautions
Patients should use Indocin with caution if they have a history of cardiovascular disease, gastrointestinal disorders, kidney impairment, or hypertension. Regular monitoring of renal function, blood pressure, and hemoglobin levels may be advised during prolonged therapy. Avoid alcohol consumption, as it may increase the risk of gastrointestinal bleeding. Use during pregnancy, especially in the third trimester, is not recommended due to potential risks to the fetus. Elderly patients may be more susceptible to adverse effects and often require lower doses.
Contraindications
Indocin is contraindicated in patients with known hypersensitivity to indomethacin, aspirin, or other NSAIDs. It should not be used in those who have experienced asthma, urticaria, or allergic-type reactions after taking NSAIDs. Additional contraindications include a history of gastrointestinal bleeding or perforation, severe heart failure, and late-stage pregnancy. It is also not recommended for use in patients with severe renal impairment or active peptic ulcer disease.
Possible side effect
Common side effects may include nausea, vomiting, diarrhea, dizziness, headache, and heartburn. More serious but less frequent side effects can involve gastrointestinal bleeding, ulceration, hypertension, edema, elevated liver enzymes, and renal dysfunction. Allergic reactions such as rash, itching, or wheezing may occur. Some patients report tinnitus or blurred vision. Any unusual or severe symptoms should be reported to a healthcare provider immediately.
Drug interaction
Indocin may interact with several medications, including other NSAIDs, anticoagulants like warfarin (increasing bleeding risk), antihypertensives (reducing their efficacy), diuretics, lithium, and methotrexate. Concomitant use with corticosteroids or selective serotonin reuptake inhibitors (SSRIs) may elevate the risk of gastrointestinal bleeding. Always inform your healthcare provider of all medications, supplements, and herbal products you are taking.
Missed dose
If a dose is missed, take it as soon as remembered, unless it is almost time for the next dose. In that case, skip the missed dose and resume the regular schedule. Do not double the dose to make up for a missed one. Consistency is important for maintaining therapeutic levels, but occasional missed doses are generally not critical; consult your prescriber for specific guidance.
Overdose
Symptoms of overdose may include severe nausea, vomiting, drowsiness, headache, blurred vision, or dizziness. In severe cases, respiratory depression, acute renal failure, or seizures can occur. If overdose is suspected, seek immediate medical attention or contact a poison control center. Treatment is typically supportive and may include gastric lavage, activated charcoal, and monitoring of vital organ function.
Storage
Store Indocin at room temperature (20–25°C or 68–77°F), in a tightly closed container, away from light, moisture, and heat. Keep out of reach of children and pets. Do not use beyond the expiration date printed on the packaging. Dispose of unused medication through a drug take-back program or according to local guidelines to prevent accidental ingestion or environmental contamination.
Disclaimer
This information is intended for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting or changing any medication regimen. Individual responses to Indocin may vary, and only a licensed practitioner can determine its appropriateness based on a patient’s specific health profile.
Reviews
Clinical studies and patient reports generally affirm Indocin’s effectiveness in managing inflammatory pain, particularly for arthritis and gout. Many users note significant improvement in mobility and pain reduction, though some report gastrointestinal side effects. It is often regarded as a strong option when other NSAIDs provide insufficient relief. Always discuss benefits and risks with your healthcare provider to ensure it aligns with your treatment goals.