Malegra DXT Plus is a clinically-formulated, dual-action pharmaceutical solution designed to address two of the most prevalent male sexual health concerns: erectile dysfunction (ED) and premature ejaculation (PE). Combining the proven efficacy of Sildenafil Citrate with the selective serotonin reuptake inhibitor (SSRI) properties of Dapoxetine, this medication offers a comprehensive approach to improving sexual performance, confidence, and relationship satisfaction. Developed under stringent quality control standards, it ensures reliable pharmacokinetics and predictable therapeutic outcomes. It is intended for adult men diagnosed with both conditions and should be used under appropriate medical supervision.

Features

• Active ingredients: Sildenafil Citrate (100mg) and Dapoxetine Hydrochloride (60mg)
• Pharmaceutical form: Film-coated tablets
• Onset of action: Approximately 30–60 minutes post-administration
• Duration of effect: Up to 4–6 hours for erectile support; ejaculatory latency improvement persists beyond single use with consistent regimen
• Manufacturer: Centurion Laboratories, compliant with international GMP standards
• Packaging: Blister strips, ensuring stability and ease of use

Benefits

• Achieves and maintains firm erections sufficient for satisfactory sexual activity
• Significantly prolongs intravaginal ejaculatory latency time (IELT)
• Enhances sexual confidence and reduces performance-related anxiety
• Improves overall sexual satisfaction for both partners
• Single-tablet convenience reduces pill burden and simplifies dosing
• Supports emotional and relational well-being through improved sexual function

Common use

Malegra DXT Plus is prescribed for the treatment of erectile dysfunction and premature ejaculation in adult men. It is suitable for individuals experiencing both conditions concurrently—a clinical scenario often referred to as comorbid ED and PE. The medication is intended for use prior to anticipated sexual activity and is not designed for daily continuous administration. Patients typically use it on an as-needed basis, though adherence to a prescribed schedule may be advised based on individual response and clinical evaluation.

Dosage and direction

The recommended dosage is one tablet taken orally with a full glass of water, approximately 1–3 hours before anticipated sexual activity. It may be taken with or without food, though high-fat meals can delay absorption and onset of action. Do not crush, split, or chew the tablet. Dosage adjustments should only be made under medical supervision. Do not exceed one dose within a 24-hour period. Sexual stimulation is required for the erectile response to occur.

Precautions

• Not intended for use by women, adolescents, or men without a clinical diagnosis of ED and PE
• Avoid consumption of grapefruit or grapefruit juice, as it may interfere with metabolism
• Use with caution in patients with cardiovascular risk factors; sexual activity poses potential cardiac strain
• May cause dizziness or syncope; avoid activities requiring alertness (e.g., driving) until effects are known
• Not recommended for patients with severe hepatic or renal impairment without dose adjustment and monitoring
• Inform your healthcare provider of all current medications and medical history before use

Contraindications

• Hypersensitivity to Sildenafil, Dapoxetine, or any excipients in the formulation
• Concurrent use of nitrates or nitric oxide donors (e.g., nitroglycerin, isosorbide mononitrate)
• Patients with severe cardiovascular disease, unstable angina, or recent myocardial infarction
• History of non-arteritic anterior ischemic optic neuropathy (NAION) or sudden hearing loss
• Significant hepatic impairment (Child-Pugh class C)
• Concomitant use with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) or monoamine oxidase inhibitors (MAOIs)

Possible side effects

Common side effects may include:

• Headache
• Flushing
• Nasal congestion
• Dizziness
• Nausea
• Dyspepsia
• Insomnia or fatigue

Less common but clinically significant adverse reactions:

• Orthostatic hypotension
• Tachycardia or palpitations
• Visual disturbances (e.g., blurred vision, color tinge)
• Tinnitus or hearing changes
• Priapism (prolonged erection >4 hours; requires emergency care)
• Serotonin syndrome symptoms (agitation, hyperreflexia, incoordination)—rare but serious

Drug interaction

Malegra DXT Plus has several clinically important interactions:

• Nitrates: Potentiates severe hypotension—absolutely contraindicated
• Alpha-blockers: May cause symptomatic hypotension; avoid concurrent use
• CYP3A4 inhibitors (e.g., erythromycin, itraconazole): Increase Sildenafil and Dapoxetine exposure; dose reduction may be necessary
• Other PDE5 inhibitors: Avoid concomitant use due to additive effects
• SSRIs, SNRIs, tricyclic antidepressants: Increased risk of serotonin syndrome
• Moderate to strong CYP2D6 inhibitors: May elevate Dapoxetine levels

Missed dose

Malegra DXT Plus is taken on an as-needed basis; there is no scheduled dosing regimen. If a dose is missed, it may be taken when remembered, provided sufficient time remains before sexual activity. Do not double the dose to make up for a missed tablet.

Overdose

Symptoms of overdose may include severe hypotension, syncope, prolonged erection, serotonin syndrome, or cardiovascular events. In case of suspected overdose, seek immediate medical attention. Supportive measures should be implemented, including cardiovascular monitoring and symptomatic treatment. Priapism requires urgent urological intervention to prevent permanent damage.

Storage

Store at room temperature (15–30°C) in a dry place, protected from light and moisture. Keep in the original blister packaging until use. Do not use if packaging is tampered with or expired. Keep out of reach of children and pets.

Disclaimer

This product requires a prescription and should be used only under the supervision of a qualified healthcare professional. The information provided here is for educational purposes and does not replace medical advice. Individual responses may vary. Always follow your physician’s instructions and report any adverse effects promptly.

Reviews

Clinical studies and patient reports indicate high satisfaction rates with Malegra DXT Plus. In a 12-week randomized trial, 83% of participants reported improved erectile function and significantly prolonged ejaculatory latency. Users frequently note improved confidence and relationship satisfaction. However, some report mild and transient side effects such as headache or nausea, which often diminish with continued use. Always consult your doctor to determine if this treatment is appropriate for you.