Assurans is a prescription medication specifically formulated to address the challenges of erectile dysfunction (ED). Its active ingredient, Sildenafil Citrate, is a well-established and clinically proven phosphodiesterase type 5 (PDE5) inhibitor that facilitates increased blood flow to the penile tissues. This mechanism is fundamental to achieving and sustaining an erection sufficient for sexual activity. By targeting the underlying physiological processes involved in erection, Assurans provides a reliable and effective therapeutic option for men seeking to improve their sexual health and overall quality of life. Treatment should be undertaken under the supervision of a qualified healthcare professional following a comprehensive medical evaluation.

Features

• Active Pharmaceutical Ingredient: Sildenafil Citrate
• Available in multiple dosage strengths (e.g., 25 mg, 50 mg, 100 mg) for tailored treatment
• Standardized film-coated tablet formulation for consistent dosing
• Rapid onset of action, typically within 30 to 60 minutes post-administration
• Duration of efficacy can last for up to 4-6 hours
• Requires sexual stimulation for effect; not an aphrodisiac

Benefits

• Achieves reliable and firm erections suitable for sexual intercourse.
• Enhances sexual confidence and reduces performance-related anxiety.
• Improves overall satisfaction for both the individual and their partner.
• Supports a healthy and active sexual life, contributing to improved relationship dynamics.
• Offers a predictable and well-characterized pharmacological profile based on extensive clinical research.

Common use

Assurans is indicated for the treatment of erectile dysfunction (ED) in adult men. Erectile dysfunction is defined as the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. The medication is used on an as-needed basis to facilitate erections when sexual stimulation occurs. It is not intended for use by women, children, or men without erectile dysfunction. A diagnosis of ED from a healthcare provider is essential before initiating treatment to rule out other underlying health conditions that may require different management.

Dosage and direction

The recommended starting dose for most patients is 50 mg taken orally approximately one hour before anticipated sexual activity. Based on efficacy and tolerability, the dose may be increased to a maximum of 100 mg or decreased to 25 mg. Dosing should be limited to a maximum of one tablet per 24-hour period. The tablet should be swallowed whole with a glass of water; it can be taken with or without food, although a high-fat meal may delay the onset of action. The medication requires sexual stimulation to be effective. Do not crush, split, or chew the tablet.

Precautions

• A thorough medical history and physical examination should be conducted to diagnose ED and assess cardiovascular health before prescribing Assurans.
• Patients with cardiovascular disease, for whom sexual activity is not advised, should generally not use Assurans.
• Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, or Peyronie’s disease), or conditions that may predispose them to priapism (e.g., sickle cell anemia, multiple myeloma, or leukemia).
• Caution is advised in patients with bleeding disorders or active peptic ulceration.
• Non-arteritic anterior ischemic optic neuropathy (NAION) has been reported rarely post-dose; patients who have experienced NAION in one eye are at increased risk of NAION in the other eye.
• Sudden decrease or loss of hearing has been reported; patients should seek immediate medical attention if these symptoms occur.
• Patients should not use Assurans in combination with any other treatments for erectile dysfunction.

Contraindications

Assurans is contraindicated in patients with:

• A known hypersensitivity to Sildenafil Citrate or any of the tablet’s excipients.
• The concurrent use of organic nitrates or nitric oxide donors (e.g., amyl nitrite) in any form, either regularly or intermittently, due to the risk of a precipitous and potentially fatal drop in blood pressure.
• The concurrent use of guanylate cyclase stimulators, such as riociguat.
• A history of serious hypersensitivity reaction requiring treatment with Sildenafil.

Possible side effect

Like all medicines, Assurans can cause side effects, although not everybody gets them. The most commonly reported side effects are mild to moderate and often transient. They may include:

• Very common (≥1/10): Headache, flushing.
• Common (≥1/100 to <1/10): Dyspepsia, nasal congestion, dizziness, visual disturbances (including blurred vision, cyanopsia, and photophobia).
• Uncommon (≥1/1,000 to <1/100): Hypotension, tachycardia, palpitations, syncope, vomiting, rash, hematuria, eye pain, photophobia, eyelid edema, conjunctival hyperemia, retinal vascular disease.
• Rare (≥1/10,000 to <1/1,000): Priapism (a prolonged and painful erection lasting more than 4 hours; requires immediate medical attention to prevent permanent tissue damage), hypersensitivity reactions (including skin rashes), sudden hearing loss, myocardial infarction, stroke. Patients should be advised to discontinue use and consult their physician if any side effect becomes severe or bothersome.

Drug interaction

Assurans can potentiate the hypotensive effects of nitrates and antihypertensive medications. Concomitant use is contraindicated with nitrates. Caution is advised when co-administered with alpha-blockers (e.g., doxazosin, tamsulosin) as this may lead to symptomatic postural hypotension. Assurans is primarily metabolized by the cytochrome P450 (CYP) isoforms 3A4 (major route) and 2C9 (minor route). Consequently, inhibitors of CYP3A4 (e.g., ketoconazole, itraconazole, ritonavir, erythromycin, grapefruit juice) may increase Sildenafil plasma concentrations, while inducers of CYP3A4 (e.g., rifampicin, carbamazepine, phenytoin, phenobarbital, St. John’s Wort) may decrease Sildenafil plasma concentrations.

Missed dose

Assurans is not intended for chronic daily dosing. It is taken on an as-needed basis. Therefore, the concept of a “missed dose” does not apply. Do not take an extra dose to make up for a missed opportunity. Adhere to the maximum dosing frequency of once per day.

Overdose

In cases of overdose, the expected clinical presentation would be an extension of the drug’s known adverse effects, including severe hypotension, syncope, and prolonged erection. Standard supportive measures should be employed as required. Given that Sildenafil is highly protein-bound, it is not expected to be dialyzable. Management of priapism should be immediate and may require corporal irrigation and, in severe cases, surgical intervention to prevent irreversible damage. In cases of severe hypotension, cardiovascular support with fluid replacement and, if necessary, vasopressor agents (e.g., phenylephrine, epinephrine) may be considered.

Storage

Store Assurans tablets below 30°C (86°F). Keep the medication in its original blister pack to protect it from light and moisture. Keep out of the reach and sight of children. Do not use Assurans after the expiry date which is stated on the packaging after “EXP.” The expiry date refers to the last day of that month. Do not dispose of medications via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required.

Disclaimer

This information is intended for educational and informational purposes only and does not constitute medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read in this product card. The information provided is based on the typical properties of the drug’s active ingredient and may not reflect the specific prescribing information for the branded product “Assurans.” Always rely on the guidance of your healthcare professional and the official patient information leaflet provided with your medication.

Reviews

• “After discussing options with my urologist, I was prescribed Assurans. The effect is consistent and reliable. It has significantly reduced the anxiety I associated with performance and has greatly improved my relationship with my partner.” – M.K., 54
• “As a physician, I appreciate the well-understood mechanism of Sildenafil. For my patients with appropriate cardiovascular health, Assurans has been a effective first-line treatment for ED. The key is proper patient selection and education.” – Dr. A.L., General Practitioner
• “I was initially hesitant, but the results have been life-changing. It works exactly as described when taken correctly. The only side effect I notice is some minor flushing, which is a small price to pay for the benefit.” – J.R., 61
• “It’s important to manage expectations. This isn’t a magic pill—it requires stimulation. But when those conditions are met, it performs its function exceptionally well. I find the 50mg dose to be the perfect balance of efficacy and minimal side effects for me.” – T.S., 48