Elimite (permethrin) 5% cream is a prescription topical medication specifically formulated to eradicate scabies mites and their eggs. As a leading scabicidal treatment, it offers targeted action against Sarcoptes scabiei var. hominis, providing relief from intense itching and preventing transmission. Clinically proven and recommended by dermatologists, this neurotoxic agent paralyzes and kills parasites upon contact while maintaining an excellent safety profile for patients aged two months and older.

Features

• Contains 5% permethrin as the active scabicidal agent
• Cream-based formulation for optimized skin absorption and residual activity
• Single-application treatment in most cases
• Prescription-strength efficacy with over 95% cure rates in clinical studies
• Minimal systemic absorption when applied topically
• Stable emulsion base prevents separation and ensures consistent dosing

Benefits

• Provides complete eradication of scabies mites and eggs with proper application
• Rapidly relieves intense itching and discomfort associated with infestation
• Breaks the transmission cycle within households and communities
• Requires only one treatment in most cases, enhancing compliance
• Suitable for children as young as two months old under medical supervision
• Prevents secondary bacterial infections from excessive scratching

Common use

Elimite is primarily indicated for the treatment of scabies infestations caused by the human itch mite (Sarcoptes scabiei). Healthcare providers may also prescribe it off-label for resistant cases of head lice (pediculosis capitis) when standard treatments prove ineffective. The medication works through direct contact with parasites, making proper application technique essential for successful eradication. Patients typically experience significant symptom improvement within 24-48 hours after treatment, though complete resolution of itching may take 2-4 weeks as the skin heals.

Dosage and direction

For scabies treatment: Thoroughly massage Elimite cream into the skin from the neck to the soles of the feet, paying particular attention to areas between fingers and toes, under nails, wrist folds, elbow creases, axillae, belt line, and gluteal cleft. Trim fingernails and apply medication beneath them. Typically leave on for 8-14 hours before washing off thoroughly with soap and water. Most cases require only one application.

For infants and elderly patients: Apply to scalp, temples, and forehead while avoiding contact with eyes and mouth.

Re-treatment: May be necessary after 7-14 days if live mites reappear. Consult healthcare provider before reapplication.

Precautions

• For external use only; avoid contact with eyes, nose, mouth, and other mucous membranes
• Do not apply to acutely inflamed skin or raw, weeping surfaces
• May exacerbate existing skin conditions such as eczema or psoriasis
• Use with caution in patients with known sensitivity to chrysanthemums or ragweed
• Wash hands thoroughly after application unless treating hands for scabies
• Sexual partners and close household contacts should be evaluated and treated simultaneously to prevent reinfestation
• Clothing, bedding, and towels used within 48 hours before treatment should be washed in hot water and dried using hot cycle

Contraindications

• Known hypersensitivity to permethrin, other pyrethroids, or pyrethrins
• History of allergic reaction to previous permethrin application
• Patients with pre-existing severe inflammatory skin conditions unless directed by physician
• Not recommended for neonates under 2 months of age due to immature skin barrier function

Possible side effects

Common (≥1% of patients):

• Temporary itching, burning, or stinging at application site
• Mild erythema or edema
• Numbness or tingling sensation
• Rash or skin irritation

Less common (<1% of patients):

• Contact dermatitis
• Skin discoloration
• Headache
• Dizziness
• Nausea

Rare but serious (require immediate medical attention):

• Severe allergic reactions (anaphylaxis)
• Difficulty breathing or swallowing
• Severe skin reactions including blistering and peeling
• Swelling of face, lips, tongue, or throat

Drug interaction

No significant systemic drug interactions have been reported due to minimal absorption. However, caution is advised when using Elimite concurrently with:

• Other topical medications that may enhance skin permeability
• Topical corticosteroids (may mask signs of infection or infestation)
• Other neurotoxic agents (theoretical potential for additive effects)
• Oil-based products that might enhance absorption

Missed dose

As Elimite is typically administered as a single application, missed dose scenarios are uncommon. If application is interrupted or washed off prematurely within the first 8 hours, reapply as soon as possible and maintain for the full recommended duration. If discovered after the recommended exposure time has passed, contact your healthcare provider for guidance. Do not apply extra medication to compensate.

Overdose

Topical overdose may result in enhanced systemic absorption leading to:

• Increased neurological symptoms (dizziness, headache, fatigue)
• Nausea and gastrointestinal discomfort
• Paresthesia (tingling sensation) beyond application sites
• Muscle twitching or incoordination

In case of accidental ingestion, seek immediate medical attention. Symptoms may include nausea, vomiting, abdominal pain, and neurological excitation followed by depression. Treatment is supportive and symptomatic.

Storage

• Store at controlled room temperature (20-25°C or 68-77°F)
• Keep tube tightly closed when not in use
• Do not freeze
• Keep away from direct heat and sunlight
• Keep out of reach of children and pets
• Discard any unused medication after treatment completion
• Do not use after expiration date printed on packaging

Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. Individual results may vary. Always consult with a qualified healthcare professional before starting any new medication. The prescribing physician should be informed of complete medical history, including allergies, current medications, and pre-existing conditions. Proper diagnosis by a healthcare provider is essential before beginning treatment.

Reviews

Clinical studies: Multiple randomized controlled trials demonstrate 85-95% efficacy rates with single application of permethrin 5% cream. A meta-analysis published in the Archives of Dermatology found permethrin superior to crotamiton and Lindane in eradication rates and safety profile.

Patient feedback: Most users report significant improvement in itching within 24-48 hours and complete resolution of symptoms within 2-4 weeks. Common praises include ease of use and effectiveness. Some users report temporary burning sensation during application.

Expert consensus: The Centers for Disease Control and Prevention (CDC) and American Academy of Dermatology recommend permethrin 5% cream as first-line treatment for scabies in most patient populations due to its efficacy and favorable safety profile compared to alternative agents.