Ginette 35 is a combined oral contraceptive pill specifically formulated for the management of polycystic ovary syndrome (PCOS) and moderate to severe acne in women. It contains a balanced combination of cyproterone acetate and ethinylestradiol, offering both anti-androgenic and estrogenic effects. This medication is prescribed to regulate menstrual cycles, reduce androgen-related symptoms, and improve dermatological conditions. Proper medical supervision is essential for its safe and effective use.

Features

• Contains 2 mg cyproterone acetate and 0.035 mg ethinylestradiol per tablet
• 21-day active pill regimen followed by a 7-day placebo interval
• Anti-androgenic properties target excess sebum production and hirsutism
• Estrogenic component supports cycle regularity and endometrial protection
• Manufactured under strict pharmaceutical quality standards
• Available in calendarized blister packs for ease of use

Benefits

• Effectively reduces sebum production, leading to clearer skin and fewer acne lesions
• Regulates menstrual cycles, decreasing the frequency of irregular or absent periods
• Diminishes symptoms of hyperandrogenism, such as unwanted facial or body hair
• Lowers the risk of ovarian cysts formation in women with PCOS
• Provides reliable contraception when taken as directed
• May improve long-term metabolic parameters in PCOS management

Common use

Ginette 35 is primarily prescribed for women experiencing androgen-dependent conditions such as polycystic ovary syndrome (PCOS) or moderate to severe acne that has not responded to topical treatments. It is also indicated for idiopathic hirsutism. The medication is suitable for women of reproductive age who require both hormonal regulation and contraception. It should not be used solely for contraceptive purposes if other anti-androgenic treatments are available and appropriate.

Dosage and direction

Take one tablet daily at approximately the same time each day for 21 consecutive days, followed by a 7-day tablet-free interval. Menstruation usually occurs during this break. Begin the next pack on the 8th day, regardless of whether bleeding has stopped. For first-time users, start on the first day of the menstrual cycle for immediate contraceptive protection. If switching from another hormonal contraceptive, follow specific transition guidelines provided by a healthcare professional. Swallow the tablet whole with water, with or without food.

Precautions

• Not intended for use during pregnancy or breastfeeding
• Regular monitoring of blood pressure, liver function, and lipid profile is recommended
• Increased risk of venous thromboembolism; discontinue use 4 weeks before elective surgery or prolonged immobilization
• May affect glucose tolerance; monitor closely in women with diabetes or predisposition
• Caution advised in women with a history of depression, migraines, or epilepsy
• Reduced efficacy may occur with gastrointestinal disturbances (vomiting or diarrhea)
• Annual gynecological examinations, including breast and cervical screening, are advised

Contraindications

• History of or current venous or arterial thrombosis/thromboembolism
• Known or suspected hormone-dependent malignancies (e.g., breast or endometrial cancer)
• Severe hepatic disease, liver tumors, or history of jaundice during pregnancy
• Undiagnosed abnormal genital bleeding
• Hypersensitivity to any component of Ginette 35
• Migraine with aura or focal neurological symptoms
• Pancreatitis or severe hypertriglyceridemia

Possible side effects

Common side effects may include nausea, headache, breast tenderness, mood changes, and breakthrough bleeding, especially during the first few cycles. Less frequently, users may experience weight changes, decreased libido, or melasma. Serious but rare adverse effects include venous thromboembolism, hypertension, gallbladder disease, and hepatic adenomas. Any persistent or severe symptoms should be reported to a healthcare provider immediately.

Drug interactions

• Antibiotics such as rifampicin may reduce efficacy
• Anticonvulsants (e.g., carbamazepine, phenytoin) can decrease hormonal levels
• Herbal supplements like St. John’s wort may interact and reduce contraceptive effect
• HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors can alter metabolism
• Cyclosporine and theophylline levels may be affected
• Consult a healthcare provider before starting any new medication or supplement

Missed dose

If a tablet is missed and less than 12 hours have passed, take it as soon as remembered and continue the schedule. If more than 12 hours have passed, take the missed tablet immediately and the next one at the usual time, even if two tablets are taken in one day. Use additional barrier contraception (e.g., condoms) for the next 7 days. If multiple tablets are missed, consult the package leaflet or a healthcare provider for specific instructions.

Overdose

Serious effects from overdose are unlikely, but may include nausea, vomiting, or withdrawal bleeding. There is no specific antidote; symptomatic treatment is recommended. Monitor for signs of thromboembolic events in cases of significant excess ingestion. Contact a poison control center or seek medical attention if concerned.

Storage

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is intended for educational purposes and does not replace professional medical advice. Always consult a qualified healthcare provider for diagnosis, treatment decisions, and individualized recommendations. Do not start, stop, or change any medication without medical supervision.

Reviews

Clinical studies and patient reports indicate that Ginette 35 is effective in reducing acne severity and regulating menstrual cycles in women with PCOS. Many users report significant improvements in skin condition and cycle regularity within 3–6 months of use. Some note initial side effects such as mild nausea or breast tenderness, which often subside after the first few cycles. Long-term satisfaction is generally high among appropriately prescribed patients, though individual experiences may vary. Always discuss personal health circumstances with a prescribing physician.